Can i ever please my parents?

I try to please my parents, My grades are good A's+B's and i gave up a relationship for them. I do my homework and my teachers are all proud of me. They say im obsessed with my looks because i wear makeup for school. I really try to please them but they always complain about me to my grandparents and also my grandparents say im a b**ch. I have even given up on my best friend because my parents didn't approve. Is it because i have fallen out with my old best mate Jess and they liked her? she was really annoying and kept copying off me also blaming me for everything!!:@